./configure: error: the HTTP cache module requires md5 functions
from OpenSSL library. You can either disable the module by using
--without-http-cache option, or install the OpenSSL library into the system,
or build the OpenSSL library statically from the source with nginx by using
--with-http_ssl_module --with-openssl=<path> options.
出现该提示是因为ssl指定路径错误问题,openssl解压设置到nginx即可