【GATK加速】作为BWA/GATK软件的替代者，Sentieon 202010版本更新细节

Sentieon最新推送版本为V2020，新版本对TNhaplotyper2模块进行了重大更新，使其能匹配4.1.9版本的Mutect2的结果，并引入了三种新算法：ContaminationModel、OrientationBias和TNfilter。在本版中，已经移除tnhaplfilter。具体更新内容如下：

新添加的功能：

Reduced memory usage when outputting CRAM files.
Maintenance update of the TNseq algorithm.
Added DNBSEQ platform to support BGI sequencers.
Improve speed of umi consensus when not outputting BI/BD tags.
Added support of BGZF compressed interval list files as well as VCF and VCF.gz files.
Modified the type of the AD, QSS and RPA FORMAT field in the VCF.
Override unlimited stack size limit in Linux to prevent Linux bug with thread local storage allocation.
Using an empty interval bed file will result in no processing done, as if the interval had 0 length.

Bug修复&#x