Modify Web.config

private void ChangeAppSettings(string key, string NewValue)  {    

  Configuration cfg;    

  cfg = System.Web.Configuration.WebConfigurationManager.OpenWebConfiguration("~");     

      KeyValueConfigurationElement setting = (KeyValueConfigurationElement)cfg.AppSettings.Settings(key);      

     if ((setting != null)) {       

   setting.Value = NewValue;         

 cfg.Save();    

  } 

 }