http://blog.csdn.net/tiantian1980/article/details/8584407
问题:The run destination My Mac 64-bit is not valid for Running the scheme 'Hello Objective-C'.
解决办法:How to change the SDK:
1) Click on the project icon in the left hand panel.
2) In the right hand panel that appears, select Build Settings » all.
3) You'll see the option to change the SDK. Screenshot
4) 把Base SDK項改成ios 5.0(这里要看你电脑的版本了)
如图: