This is one of the various errors that appear when you are debugging and may haunt you until you do the following fix:-
1. In the Internet Explorer, "Tools" Menu, select "Internet Options".
2. Switch to "Security" Tab.
3. Click on "Internet" (The Globe Icon. Its actually the default selected).
4. Click on "Custom Level" in the bottom.
5. Scroll down to find the "User Authentication" section.
6. Select "Automatic logon with current username and password".
7. Click "Ok" twice to exit.
This should solve the issue.
Please note that this resolution is specific only if you get the exact error message as mentioned in the beginning of this article. There are various reasons you get the "Unable to start debugging on the webserver". For a complete list of solutions, please check http://msdn.microsoft.com/library/default.asp?url=/library/en-us/dv_vstechart/html/vsdebug.asp
Cheers and Happy Programming !!!