"Proto" is short for protocol, which is either TCP or UDP. "Recv-Q" and "Send-Q" mean receiving queue and sending queue. These should always be zero; if they're not you might have a problem. Packets should not be piling up in either queue, except briefly, as this example shows:
tcp 0 593 192.168.1.5:34321 venus.euao.com:smtp ESTABLISHED
That happened when I hit the "check mail" button in KMail; a brief queuing of outgoing packets is normal behavior. If the receiving queue is consistently jamming up, you might be experiencing a denial-of-service attack. If the sending queue does not clear quickly, you might have an application that is sending them out too fast, or the receiver cannot accept them quickly enough.
"Local address" is either your IP and port number, or IP and the name of a service. "Foreign address" is the hostname and service you are connected to. The asterisk is a placeholder for IP addresses, which of course cannot be known until a remote host connects. "State" is the current status of the connection. Any TCP state can be displayed here, but these three are the ones you want to see。