SMTP传输优化: 使用独立的服务器作为SMTP邮件网关(推荐)
调整Mailroot目录存放的位置(推荐): How to change the Exchange 2000 SMTP Mailroot directory location ->http://support.microsoft.com/default.aspx?scid=kb;en-us;318230  How to change the Exchange 2003 SMTP Mailroot folder location ->http://support.microsoft.com/default.aspx?scid=kb;en-us;822933
  SMTP Max Objects(不推荐): SMTP队列所能容纳的邮件数量,每一封在SMTP队列中的邮件都会消耗4KB内存,调小此参数,有助于节省RAM利用率.  仅在服务器需要处理非常大量的邮件队列时,才启用此优化 
Location: HKEY_LOCAL_MACHINE\Software\Microsoft\Exchange\Mailmsg
Parameter: MaxMessageObject(REG_DWORD)
Default setting: Not present but defaults to 0x000186a0(100000)
When to change: Adjust if the Exchange server is running out of memory because the number of incoming messages is too great for the server to process
AD访问优化: GC与Exchange比例: 1:4(GC和Exchange Server的CPU比例)
当DC服务器满足如下的条件时,应该在boot.ini中启动/3GB参数,以提高DC的数据库性能: OS=Windows 2000 Adv or Windows 2003  RAM>=2GB  http://support.microsoft.com/default.aspx?scid=kb;en-us;328882
当DC和Exchange共存在同一台服务器上时: DC进程的优先级高于Exchange,在繁忙时,发给DC的请求先被处理,因此可能对Exchange有影响.  Exchange必需有DC的本地登录权限,可能有额外的安全问题  Exchange智能的选择DC/GC,可能并不优先使用同一台服务器上的DC/GC功能,不能够借此来达到容错和附载均衡的目的 
  使用Dsadiag命令来诊断DC/GC的访问问题 ->http://www.windowssitpro.com/Article/ArticleID/21621/21621.html?Ad=1
网络优化: 100M Full Duplex,非常重要!!!  ->所有DC和Exchange服务器的NIC Port  上面这些Port所连接的Switch Port
   数据库优化: 目的: 减低内存消耗  减轻磁盘I/O压力
  存储组和数据库: 4*5   在存储组没有满5个数据库之前,不要创建新的存储组(每个存储组实例都会消耗大量内存)
Store.exe的虚拟地址空间: 虚拟地址空间和内存分配,碎片的产生原因
Log中的9582和9584错误: Monitoring for Exchange 2000 memory fragmentation ->http://support.microsoft.com/default.aspx?scid=kb;en-us;296073
Your computer may slow or stop responding and repeatedly log event IDs 9582 and 1160 in Exchange 2000 Server ->http://support.microsoft.com/default.aspx?scid=kb;en-us;838233
  How to troubleshoot virtual memory fragmentation in Exchange Server 2003 and Exchange 2000 Server ->http://support.microsoft.com/default.aspx?scid=kb;en-us;325044
  优化Store.exe虚拟地址空间的三个步骤: /3GB: 当OS为Win2k Adv或Win2k3, 并且有1GB以上的物理内存时,应该在boot.ini中启用此参数  Exchange 2000 requires /3GB switch with more than 1 gigabyte of physical RAM ->http://support.microsoft.com/default.aspx?scid=kb;en-us;266096 
/USERVA=2970: 当Exchange运行在Windows 2003上时,此参数需要在boot.ini中启用  Using the /Userva switch on Windows Server 2003-based computers that are running Exchange Server ->http://support.microsoft.com/default.aspx?scid=kb;en-us;810371 
     HeapDeCommitFreeBlockThreshold: 服务器有1GB物理内存时,此参数应在注册表中设定,以降低虚拟地址空间的碎片  How to troubleshoot virtual memory fragmentation in Exchange Server ->http://support.microsoft.com/default.aspx?scid=kb;en-us;325044  The"HeapDecommitFreeBlockThreshold"registry key ->http://support.microsoft.com/default.aspx?scid=kb;en-us;315407
操作系统优化(page file/defragment): Registry fragment will kill your server: 使用Page Defrag来检测系统碎片 ->http://www.sysinternals.com/Utilities/PageDefrag.html