signature=064ebf03328c4e6973ccd08f9b64fb80,A novel genome signature based on inter-nucleotide distan...

本文介绍了一种新的可视化方法——INP方法,通过将碎片序列转换为内核间距离谱并运用主成分分析进行分析,成功地在二维散点图中区分不同物种来源。实验结果表明,INP方法在三个公开基准数据集上的表现优异,为代谢组数据分析提供了有力工具。
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摘要:

There has been a growing interest in visualization of metagenomic data. The present study focuses on the visualization of metagenomic data using inter-nucleotide distances profile. We first convert the fragment sequences into inter-nucleotide distances profiles. Then we analyze these profiles by principal component analysis. Finally the principal components are used to obtain the 2-D scattered plot according to their source of species. We name our method as inter-nucleotide distances profiles (INP) method. Our method is evaluated on three benchmark data sets used in previous published papers. Our results demonstrate that the INP method is good, alternative and efficient for visualization of metagenomic data.

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