摘要:
Transposable elements (TEs) are mobile and mostly repetitive genetic elements, which are ubiquitously distributed throughout all kingdoms. They are able to change their position within the genome and therefore have a huge impact on genome diversity. They are very diverse in structure and transposition mechanism. These characteristics led to a special classification system: class I TEs transpose via an RNA intermediate and class II elements transpose directly on DNA-level. Additionally TEs can be used as tools for random mutagenesis. Their impact on gene expression as well as their ability to cause mutations makes them an interesting tool. The use of TEs for random mutagenesis would aid gene characterization in many filamentous fungi for instance in pathogenic or biotechnological important strains.
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