signature=f25051b5f5ec9a850b58591cbeb3ac05,5,11-dihydrodibenzo[b,e][1,4]-thiazepines useful as gastr...

摘要:

The invention provides compounds of the formula: ##STR1## wherein k is 1, 2 or 3; m is 1, 2 or 3; n is 1, 2 or 3; p is 0, 1 or 2; X is O, S or a direct link, with the proviso that when X is O or S, n is 2 or 3; R 1 is H or C 1 -C 4 alkyl; and R 2 is an optionally substituted phenyl or heteroaryl group; and pharmaceutically acceptable salts thereof. These compounds are useful for the treatment of motility disorders, particularly those of the gut such as irritable bowel syndrome.

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