报错：（1193, "Unknown system variable 'tx_isolation'"）

pip install -i https://pypi.tuna.tsinghua.edu.cn/simple --upgrade sqlalchemy --ignore-installed

这个安装以后会报错
提示如下
WARNING: You are using pip version 19.3.1; however, version 20.0.2 is available.
You should consider upgrading via the ‘python -m pip install --upgrade pip’ command.
然后只能按提示更新pip

python -m pip install -i https://pypi.tuna.tsinghua.edu.cn/simple --upgrade pip

重新打开spyder
可以正常了终于