活性氧Pargyline (hydrochloride)，CAS No. 306-07-0

产品名称：活性氧Pargyline (hydrochloride)，CAS No. 306-07-0

产地：西安
规格：1mg 5mg 10mg
纯度：99%
用途：仅用于科研
状态：固体/粉末
储藏条件：冷藏-20℃
温馨提示：仅用于科研，不能用于人体实验！
说明：提供使用说明，核磁图谱，包装，价格，产地，制备方法，应用，稳定性，溶解度，简单合成等各种信息　　

Pargyline is an irreversible inhibitor of monoamine oxidase (MAO; Kis = 15 and 1.8 μM for MAO-A and MAO-B, respectively).1 At 10 mg/kg i.v., pargyline induces a moderate decrease of systolic blood pressure in unanaesthetized hypertensive rats but not normotensive WKR or Sprague-Dawley rats.2 The correlation between the fall of blood pressure and the inhibition of brain MAO suggests that the accumulation of amine in brain is responsible for the fall in pressure.3 Reactive oxygen species-mediated monocyte hypertrophy is prevented by pargyline at a concentration of 10 µM.4 Formulations containing pargyline have been used to treat moderate hypertension.

 

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编辑：XAQYBIO HAO，2023年4月15日。