string address="E:\\1.tif";//tif文件物理路径
System.IO.FileStream stream = System.IO.File.OpenRead(address);
Bitmap bmp = new Bitmap(stream);
System.Drawing.Image image = bmp;//得到原图
//创建指定大小的图
System.Drawing.Image newImage = image.GetThumbnailImage(424, 600, null, new IntPtr());
Graphics g = Graphics.FromImage(newImage);
g.DrawImage(newImage, 0, 0, newImage.Width, newImage.Height);
//将原图画到指定的图上
g.Dispose();
stream.Close();
newImage.Save(Server.MapPath(".") + "\\showFax.jpg", ImageFormat.Jpeg); //这里必须是物理路径