DOTA-Maleimide，DOTA-马来酰亚胺，能够与生物分子中的巯基反应

文章关键词：DOTA-马来酰亚胺，DOTA-Maleimide，DOTA Mal，1006711-90-5

一、基本信息

【性质简介】：DOTA Maleimide, also known as DOTA maleimide, is a special compound with a core structure composed of DOTA (tetraazacyclododecane) and maleimide. DOTA, as a macrocyclic ligand, possesses excellent coordination ability and can efficiently complex with various metal ions, forming structurally stable and high-performance complexes. This complex has shown broad application prospects in fields such as biomedical science, materials science, and environmental monitoring. Maleimide, as another key component of DOTA Maleimide, is a highly active biological group. With its unique reaction properties, it can specifically bind with thiol groups in biomolecules, thereby achieving a tight connection between the probe and biomolecules. This kind of connection not only helps to gain a deeper understanding of the structure and function of biomolecules, but also provides strong support for achieving precise diagnosis and treatment of diseases. In the field of biomedicine, DOTA Maleimide is a novel biological probe with high sensitivity and specificity.

【中文名】：DOTA-马来酰亚胺

【英文名】：DOTA-Maleimide，DOTA Mal

【CAS号】：1006711-90-5

【化学式】：C22H34N6O9·HPF6·TFA

【分子量】：786.5

【结构式】：

 

​二、详情介绍

【外观】：固体/粉末

【溶解性】：溶于大部分有机溶剂

【规格】：10mg，25mg，50mg

【纯度】：95%+

【储存条件】：本品应密封避光，储存于阴凉、干燥、通风处，避免反复冻融，储液应该立即使用

【注意事项】：试剂仅用于科学研究或者工业应用等非医疗目的，非药用，非食用！

三、相关试剂

Dota-ggga

Cyclo(-RGDfK)

cyclic（RGDyK）

Azido cyclic（RGDyK）

Pentynoic cyclic RGDyK

Azido-ApoPep-1

Azido-TAT

NOTA-3P-TATE-RGD

Cinnamycin-PEG3-NOTA

Folate-nota Methyltetrazine-DOTA

Duramycin-Cy5

HYNIC-Gly3-duramycin

NOTA-NEB

ICG-NOTA

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