824426-32-6，叠氮乙酸 NHS 酯，叠氮基可以通过点击化学与炔烃反应

文章关键词：Azidoacetic Acid NHS Ester，叠氮乙酸 琥珀酰亚胺酯，叠氮乙酸 NHS 酯，824426-32-6

一、基本信息

【性质简介】：Azidoacetic acid NHS ester， Behind this chemical term, there is rich chemical knowledge and potential application value. This compound uniquely combines the two functional groups of azide and NHS ester, making it exhibit unique charm in biomarkers and synthetic chemistry. Firstly, the azide group, which has unique reactivity, can efficiently and selectively react with various compounds through click chemistry. Whether it's with active alkynes or with BCN Specific functional groups such as DBCO, TCO, Tetrazine, and azide groups can react quickly and accurately to form stable triazole bonds. This reaction method is not only easy to operate, but also has mild conditions, making it widely applicable in fields such as biomolecular modification and drug synthesis. And NHS esters, as another important functional group, play an irreplaceable role in protein labeling and oligonucleotide modification. It can react with the primary amine (- NH2) group in proteins, thereby achieving specific labeling of proteins. Meanwhile, NHS esters can also react with amine modified oligonucleotides and other amine containing molecules, endowing these molecules with new functions or properties. This labeling method not only has high sensitivity and specificity, but also maintains the biological activity of the labeled molecule, making it of great application value in biomedical research and drug development.

【中文名】：叠氮乙酸 琥珀酰亚胺酯，叠氮乙酸 NHS 酯

【英文名】：Azidoacetic Acid NHS Ester

【CAS号】：824426-32-6

【化学式】：C6H6N4O4

【分子量】：198.13

【结构式】：

 

​二、详情介绍

【外观】：固体/粉末

【溶解性】：溶于大部分有机溶剂

【规格】：1g、5g、10g等

【纯度】：95%+

【储存条件】：本品应密封避光，储存于阴凉、干燥、通风处，避免反复冻融，储液应该立即使用

【注意事项】：试剂仅用于科学研究或者工业应用等非医疗目的，非药用，非食用！

三、相关试剂

Azide-PEG3-Tos

Azide-PEG6-Tos

Azide-PEG5-Tos

Azide-PEG4-Tos

Azide-PEG7-Tos

Azide-PEG12-Tos

5-TAMRA Azide，5-TAMRA-N3，TAMRA Azide,5-isomer

PEP Azide

Azido-PEG1-hydrAzide HCl Salt

BDP R6G Azide

5-TAMRA-PEG3-Azide，TAMRA-PEG3-N3

2-Azidoacetic acid，Azide Acetic Acid

Azide-PEG-hydrAzide，N3-PEG-hydrAzide，MW：5000

Azide-PEG-hydrAzide，N3-PEG-hydrAzide，MW：3400

本文整理分享来自于小编zmy