中文名:环(亮氨酸-苏氨酸)
英文名:Cyclo(Leu-Thr)
cyclo(LT)(main chain cyclo)
CAS:N/A
所属分类:Bifunctional chelato
分子式:C10H18N2O3
分子量:214.26
等电点(PI):6.11
pH=7.0时的净电荷数:-0.02
平均亲水性:-1.1
疏水性值:1.55
一、结构式:
二、反应机理:
Cyclo(Leu-Thr)是一种人工合成的二肽化合物,由L-Leucine和L-Threonine通过肽键连接而成。环二肽又叫2,5-二酮哌嗪的衍生物,作为环肽成员中比较小的一类环肽,专肽生物有部分环二肽,也可以根据实验需求,定制含D型与L型,S与R构型的氨基酸。它具有抑制蛋白质合成和诱导细胞凋亡的作用。Cyclo(Leu-Thr)的结构与天然存在的胰岛素无关。Cyclo(Leu-Thr)通过抑制核糖核蛋白激酶的活性,抑制核糖体合成蛋白质的过程。
Cyclo (Leu Thr), a cyclic dipeptide, contains Leucine and Threonine. Threonine is an organic substance, with the chemical formula of C4H9NO3 and the Molecular formula of NH2-CH (COOH) - CHOH-CH3. Its chemical name is α— Amino - β— Hydroxybutyric acid has four Stereoisomerism, and only L-type has biological activity.
三、产品形式:
外观:固体/粉末
规格种类:1g,5g,10g
纯度:95%,详情可在线咨询
发货:每日订单截止时间为16点整,部分城市可到17点整,因超过截止时间造成当日不能发货的将于次日安排顺丰进行发货。
注意事项:
本品应密封避光,储存于阴凉,干燥,通风处。
避免频繁解冻,现配现用,-20℃以下冰冻
四、同类型相关试剂:
Cyclo(-Pro-Gly)3
cyclo(Arg-Gly-Asp-D-Tyr-Val)
Cyclo(-Arg-Ala-Asp-D-Phe-Lys)
cyclo(Arg-Gly-Asp-D-Phe-Cys)
Cyclo(Pro-Trp)
Boc-Pro-Thr-OH
H-Pro-Thr-His-Ile-Lys-Trp-Gly-Asp-OH
Cyclo(-Arg-Gly-Asp-D-Tyr-Lys)
Cyclo(-Gly-Arg-Gly-Asp-Ser-Pro)
cyclo(Ala-His)
cyclo(D-Ala-Pro)
Cyclo(-Arg-Gly-Asp-D-Tyr-Lys)
Cyclo(-Arg-Ala-Asp-D-Tyr-Lys)
Cyclo(Hpro-Leu)
cyclo(Ala-Gln)
cyclo(Ala-Glu)
Cyclo(-Hyp-Gly)
Cyclo(Pro-D-Phe-Leu-Orn-Val-Pro-D-Phe-Leu-Orn-Val-)
Cyclo(-Gly-Arg-Gly-Glu-Ser-Pro)
cyclo(Ala-Ala)
cyclo(Ala-Gly)
cyclo(Ala-Ser)
Cyclo(-Gly-Arg-Gly-Asp-Ser-Pro)
Cyclo(-Trp-Pro)
Boc-Pro-Thr-OBzl