环(甘氨酰-L-亮氨酰)，Cyclo(Leu-Gly)，5845-67-0，cyclo(-leu-gly)

中文名：环(甘氨酰-L-亮氨酰)

英文名：Cyclo(-Leu-Gly)

L-Leucylglycine diketopiperazine

MORPHINE TOLERANCE PEPTIDE

(3S)-3-Isobutyl-2,5-piperazinedione

2,5-Piperazinedione, 3-(2-methylpropyl)-, (3S)-

MORPHIN,TOLERANCE PEPTIDE

Cyclo(Leu-Gly)

3-isobutylpiperazine-2,5-quinone

(3S)-3-Isobutylpiperazine-2,5-dione

cyclo(-leu-gly)

CYCLO(-GLY-LEU)

CAS：5845-67-0

沸点：442.9±38.0 °C at 760 mmHg

闪点：207.4±26.9 °C

熔点：255°C

密度：1.0±0.1 g/cm3

一、Product parameters：

1.Molecular formula：C8H14N2O2

2.Molecular weight：170.209

3.Packaging specification：1g、5g、10g, flexible packaging, including 100mg packaging and 500mg 1g and 5g large packaging

Product structure：

 

二、Reaction characteristics：

CYCLO(-GLY-LEU)，环肽氨基酸衍生化合物，是一种神经肽,可下调多巴胺(DA)受体并减弱多巴胺能超敏性。环(甘氨酰-L-亮氨酸)具有预防迟发性和/或L-DOPA(HY-N0304)诱导的运动障碍的潜力。

Cyclo(-Leu-Gly)是一种具有生物活性的人工合成的环状肽，由两个氨基酸Leu和Gly通过肽键连接而成。Cyclo(-Leu-Gly)的化学结构是由两个氨基酸通过肽键连接而成的环状肽，其中Leu和Gly是构成该环状肽的两个氨基酸。这种环状结构使得Cyclo(-Leu-Gly)具有良好的稳定性和较低的代谢率，因此能够在体内较长时间地保持活性。Cyclo(-Leu-Gly)的生物活性主要表现在其与某些神经递质受体的相互作用上。

三、Matters for use：

It is sensitive to light and temperature. In order to use the reagent effectively, the material should always be kept in a low temperature dry condition, away from light, and avoid frequent thawing and freezing.

四、storage conditions:

Store at - 20 ℃ as much as possible. If conditions permit, the material can be treated under inert gas to obtain better stability of the reagent.

 

【Reagent related products】

Cyclo(-Leu-Leu)

Cyclo(Leu-Ser)

Cyclo(Leu-Thr)

cyclo(Arg-Gly-Asp-D-Tyr-Cys)

Cyclo(-Leu-Gly)

Cyclo(Ala-Leu)

Cyclo(-Leu-Val)

Cyclo(Ile-Leu)

Cyclo(-Leu-Leu)

cyclo(Arg-Gly-Asp-D-Phe-Cys)

Cyclo(Ile-Leu)

cyclo(Trp-Tyr)

cyclo(Trp-Trp)

Cyclo(Leu-Ser)

Cyclo(Leu-Thr)

cyclo(Trp-Tyr)

cyclo(D-Trp-Tyr)

CYCLO(-PHE-PRO)

cyclo(Trp-Trp)

Cyclo(leu-leu-trp-glu-ala)

CYCLO(-PHE-SER)

Cyclo(Ala-Leu)

Cyclo(-Leu-Val)

Cyclo(Phe-Pro)

Cyclo(-Phe-Trp)

cyclo(D-Trp-Tyr)

Cyclo(Phe-Gly)

cyclo(Ser-Tyr)

cyclo(Ser-Ser)