酰胺键成环试剂，862772-11-0，Cyclo(-Arg-Gly-Asp-D-Phe-Cys)

中文名：N/A

英文名：cyclo(Arg-Gly-Asp-D-Phe-Cys)

Cyclo(-Arg-Gly-Asp-D-Phe-Cys)

cyclo(RGDfC)

cyclo(RGD-DPhe-C)

CAS：862772-11-0

等电点(PI)：8.55

平均亲水性：0.625

pH=7.0时的净电荷数：0.94

疏水性值：-0.62

density： 1.55±0.1 g/cm3(Predicted)

Acidity coefficient：(pKa)4.01±0.10(Predicted)

一、Product parameters：

1.Molecular formula：C24H34N8O7S1

2.Molecular weight：578.64

3.Packaging specification：1g、5g、10g, flexible packaging, including 100mg packaging and 500mg 1g and 5g large packaging

Product structure：

​二、Reaction characteristics：

RGDtumor靶向肽，环肽科研试剂cyclo(Arg-Gly-Asp-D-Phe-Cys)（Cyclo-RGDfC）是一种与αvβ3具有高亲和力的环状RGD肽。Cyclo（Arg-Gly-Asp-D-Phe-Cys）可用于tumor研究。

cyclo(Arg-Gly-Asp-D-Phe-Cys)是一种有效的选择性血管内皮生长因子受体（VEGFR）拮抗剂，可抑制肿瘤细胞的增殖和迁移。VEGFR在许多肿瘤中高表达，因此成为了抗肿瘤药物开发的热门靶点。而cyclo(Arg-Gly-Asp-D-Phe-Cys)正是针对这一靶点设计的特异性抑制剂。

三、Matters for use：

It is sensitive to light and temperature. In order to use the reagent effectively, the material should always be kept in a low temperature dry condition, away from light, and avoid frequent thawing and freezing.

四、storage conditions:

Store at - 20 ℃ as much as possible. If conditions permit, the material can be treated under inert gas to obtain better stability of the reagent.

【Reagent related products】

Cyclo(-Leu-Val)

Cyclo(Ile-Leu)

Cyclo(-Leu-Leu)

Cyclo(-Arg-Gly-Asp-D-Phe-Lys) trifluoroacetate salt

Cyclo(-Arg-Ala-Asp-D-Tyr-Lys)

FAP-2286

DOTA-E-[cyclo(RGDfK(Acp))]2

cyclo(Arg-Gly-Asp-D-Tyr-Val)

cyclo(Arg-Gly-Asp-D-Phe-Cys)

Cilengitide trifluoroacetate sal

Cyclo(-Arg-Ala-Asp-D-Phe-Lys)

Cyclo(-Leu-Gly)

Cyclo(-Arg-Gly-Asp-D-Phe-Val) trifluoroacetate salt

Cyclo(-Arg-Gly-Asp-D-Phe-Glu) trifluoroacetate salt

cyclo(Arg-Gly-Asp-D-Tyr-Cys)

Cyclo(Ala-Leu)

Cyclo(Leu-Ser)

Cyclo(Leu-Thr)

PSMA I&T,DOTAGA-DTyr(3I)-DPhe-DLys(Sub-Lys-urea-Glu)

cyclo(RGDFK(DOTA)）

Cyclo(Arg-Gly-Asp-D-Phe-Val) TFA

Cyclo(-Arg-Ala-Asp-D-Phe-Cys) trifluoroacetate salt

Cyclo(-Arg-Gly-Asp-D-Tyr-Lys) trifluoroacetate salt

本篇图文信息均由陕西新研博美生物科技小编木木提供，如需了解详细烦请联系！