中文名:DOTA-五聚乙二醇-C4-二苯并环辛炔
英文名:DOTA-PEG5-C4-DBCO,DOTA PEG5 C4 DBCO
Molecular formula:C49H71N7O14
Molecular weight:982.14
Purity:95%+
Appearance:solid/powder
Matters for use:
It is sensitive to light and temperature. In order to use the reagent effectively, the material should always be kept in a low temperature dry condition, away from light, and avoid frequent thawing and freezing.
storage conditions:
Store at - 20 ℃ as much as possible. If conditions permit, the material can be treated under inert gas to obtain better stability of the reagent.
Packing specification:10mg,25mg,50mg
结构式:
产品介绍:
DOTA-PEG5-C4-DBCO,作为一种由DOTA(1,4,7,10-四氮杂环十二烷-1,4,7,10-四乙酸)、PEG5(五聚乙二醇)和C4-DBCO(带有一个C4间隔基的二苯并环辛炔)组成的化合物,在生物学和化学领域展现出了广泛的应用前景。本文将详细介绍DOTA-PEG5-C4-DBCO的性质特点、应用以及使用注意事项。
作为一种多功能的生物分子连接剂,DOTA-PEG5-C4-DBCO可用于构建复杂的生物分子结构或实现生物分子的功能化修饰。例如,在PROTAC(蛋白水解靶向嵌合体)分子的合成中,DOTA-PEG5-C4-DBCO可以作为接头连接两个不同的配体,一个是E3泛素连接酶的配体,另一个是靶蛋白的配体。
C4-DBCO部分具有高效的点击反应能力,可以与含有叠氮基团的分子进行特异性的反应。这种反应通常在无铜条件下进行,无需催化剂,是一种有力的生物共轭工具。这使得DOTA-PEG5-C4-DBCO在生物分子的连接和修饰中表现出色。
同类型相关产品:
DBCO-PEG12-Biotin Conjugate
DBCO-PEG4-Biotin
DBCO-PEG4-Desthiobiotin
DBCO-PEG4-NH-Boc
DBCO-NH-Boc
DBCO-PEG4-Acid
DBCO-NHCO-PEG4-NH-Boc
DBCO-Maleimide
DBCO-PEG4-Maleimide
Sulfo DBCO-Maleimide
Diazo Biotin-DBCO
DBCO-S-S-PEG3-Biotin
DBCO-S-S-PEG3-Biotin
(文章资料汇总来源于:陕西新研博美生物科技小编木木)