具有特定的空间结构,二肽化合物,环二肽Cyclo(Leu-Thr)

中文名:环(亮氨酸-苏氨酸)

英文名:Cyclo(Leu-Thr)

cyclo(LT)(main chain cyclo)

CAS:N/A

所属分类:Bifunctional chelato

等电点(PI):6.11

pH=7.0时的净电荷数:-0.02

平均亲水性:-1.1

疏水性值:1.55

Molecular formula:C10H18N2O3

Molecular weight:214.26

Purity:95%+

Appearance:solid/powder

Matters for use:

It is sensitive to light and temperature. In order to use the reagent effectively, the material should always be kept in a low temperature dry condition, away from light, and avoid frequent thawing and freezing.

storage conditions:

Store at - 20 ℃ as much as possible. If conditions permit, the material can be treated under inert gas to obtain better stability of the reagent.

Packing specification:1g,5g,10g

结构式:

 

产品介绍:

Cyclo(Leu-Thr)是一种人工合成的二肽化合物,由L-Leucine和L-Threonine通过肽键连接而成。环二肽又叫2,5-二酮哌嗪的衍生物,作为环肽成员中比较小的一类环肽,专肽生物有部分环二肽,也可以根据实验需求,定制含D型与L型,S与R构型的氨基酸。它具有抑制蛋白质合成和诱导细胞凋亡的作用。Cyclo(Leu-Thr)的结构与天然存在的胰岛素无关。Cyclo(Leu-Thr)通过抑制核糖核蛋白激酶的活性,抑制核糖体合成蛋白质的过程。

Cyclo (Leu Thr), a cyclic dipeptide, contains Leucine and Threonine. Threonine is an organic substance, with the chemical formula of C4H9NO3 and the Molecular formula of NH2-CH (COOH) - CHOH-CH3. Its chemical name is α— Amino - β— Hydroxybutyric acid has four Stereoisomerism, and only L-type has biological activity.

(文章资料汇总来源于:陕西新研博美生物科技有限公司小编木木)

 

同类型相关产品:

Cyclo(-Pro-Gly)3

cyclo(Arg-Gly-Asp-D-Tyr-Val) 

Cyclo(-Arg-Ala-Asp-D-Phe-Lys)

cyclo(Arg-Gly-Asp-D-Phe-Cys)

Cyclo(Pro-Trp)

Boc-Pro-Thr-OH

H-Pro-Thr-His-Ile-Lys-Trp-Gly-Asp-OH

Cyclo(-Arg-Gly-Asp-D-Tyr-Lys)

Cyclo(-Gly-Arg-Gly-Asp-Ser-Pro)

cyclo(Ala-His)

cyclo(D-Ala-Pro)

Cyclo(-Arg-Gly-Asp-D-Tyr-Lys)

Cyclo(-Arg-Ala-Asp-D-Tyr-Lys)

Cyclo(Hpro-Leu)

cyclo(Ala-Gln)

cyclo(Ala-Glu)

Cyclo(-Hyp-Gly)

Cyclo(Pro-D-Phe-Leu-Orn-Val-Pro-D-Phe-Leu-Orn-Val-)

Cyclo(-Gly-Arg-Gly-Glu-Ser-Pro)

cyclo(Ala-Ala)

cyclo(Ala-Gly)

cyclo(Ala-Ser)

Cyclo(-Gly-Arg-Gly-Asp-Ser-Pro)

Cyclo(-Trp-Pro)

Boc-Pro-Thr-OBzl

备注:本产品仅用于科研,不能用于人体治疗或家庭备药。

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