中文名:N/A
英文名:cyclo(Arg-Gly-Asp-D-Phe-Cys)
Cyclo(-Arg-Gly-Asp-D-Phe-Cys)
cyclo(RGDfC)
cyclo(RGD-DPhe-C)
CAS:862772-11-0
分子式:C24H34N8O7S1
分子量:578.64
等电点(PI):8.55
平均亲水性:0.625
pH=7.0时的净电荷数:0.94
疏水性值:-0.62
density: 1.55±0.1 g/cm3(Predicted)
Acidity coefficient:(pKa)4.01±0.10(Predicted)
结构式:
反应机理:
RGDtumor靶向肽,环肽科研试剂cyclo(Arg-Gly-Asp-D-Phe-Cys)(Cyclo-RGDfC)是一种与αvβ3具有高亲和力的环状RGD肽。Cyclo(Arg-Gly-Asp-D-Phe-Cys)可用于tumor研究。
cyclo(Arg-Gly-Asp-D-Phe-Cys)是一种有效的选择性血管内皮生长因子受体(VEGFR)拮抗剂,可抑制肿瘤细胞的增殖和迁移。VEGFR在许多肿瘤中高表达,因此成为了抗肿瘤药物开发的热门靶点。而cyclo(Arg-Gly-Asp-D-Phe-Cys)正是针对这一靶点设计的特异性抑制剂。
如果想要详细了解相关内容,可以联系陕西新研博美生物科技有限公司小编木木
产品形式:
1.外观为固体/粉末
2.溶于大部分有机溶剂,溶于水
3.纯度标准95+,详情可在线咨询
保存建议:避免反复冻融,避光避湿保存,储液应该立即使用,-20℃以下冰冻。从冰箱取出产品后,置于室温回温至少30min-1h,再开盖,以避免受潮。
同类型试剂:
Cyclo(-Leu-Val)
Cyclo(Ile-Leu)
Cyclo(-Leu-Leu)
Cyclo(-Arg-Gly-Asp-D-Phe-Lys) trifluoroacetate salt
Cyclo(-Arg-Ala-Asp-D-Tyr-Lys)
FAP-2286
DOTA-E-[cyclo(RGDfK(Acp))]2
cyclo(Arg-Gly-Asp-D-Tyr-Val)
cyclo(Arg-Gly-Asp-D-Phe-Cys)
Cilengitide trifluoroacetate sal
Cyclo(-Arg-Ala-Asp-D-Phe-Lys)
Cyclo(-Leu-Gly)
Cyclo(-Arg-Gly-Asp-D-Phe-Val) trifluoroacetate salt
Cyclo(-Arg-Gly-Asp-D-Phe-Glu) trifluoroacetate salt
cyclo(Arg-Gly-Asp-D-Tyr-Cys)
Cyclo(Ala-Leu)
Cyclo(Leu-Ser)
Cyclo(Leu-Thr)
PSMA I&T,DOTAGA-DTyr(3I)-DPhe-DLys(Sub-Lys-urea-Glu)
cyclo(RGDFK(DOTA))
Cyclo(Arg-Gly-Asp-D-Phe-Val) TFA
Cyclo(-Arg-Ala-Asp-D-Phe-Cys) trifluoroacetate salt
Cyclo(-Arg-Gly-Asp-D-Tyr-Lys) trifluoroacetate salt
注意点:仅用于科学研究或者工业应用等非医疗目的,不可用于人类,非药用,非食用