血管紧张素-1 转化酶 (ACE) 抑制剂,IC₅₀ 14.2 μM。Ala-Tyr 已被用作大鼠静脉营养中的酪氨酸来源。二肽 AY 是肝衰竭患者胃肠外营养的有效 Tyr 来源。
Inhibitor of angiotensin-1 converting enzyme (ACE), IC₅₀ 14.2 μM. Ala-Tyr has been used as a tyrosine source in intravenous nutrition of the rat. The dipeptide AY is an efficient Tyr source for the parenteral nutrition of patients with hepatic failure.
编号: 160490
中文名称: 二肽Ala-Tyr
英文名: Ala-Tyr
CAS号: 3061-88-9
单字母: H2N-AY-OH
三字母: H2N-Ala-Tyr-COOH
氨基酸个数: 2
分子式: C12H16N2O4
平均分子量: 252.27
精确分子量: 252.11
等电点(PI): 9.36
pH=7.0时的净电荷数: 0.97
平均亲水性: -1.95
疏水性值: 0.45
来源: 人工化学合成,仅限科学研究使用,不得用于人体。
纯度: 95%、98%
盐体系: 可选TFA、HAc、HCl或其它
生成周期: 2-3周
储存条件: 负80℃至负20℃
标签: 抑制剂相关肽 二肽(Dipeptide) 食品研究与营养
DOI 名称
10.1021/jf0705670 Peptide with angiotensin I-converting enzyme inhibitory activity from hydrolyzed corn gluten meal 下载
10.1063/1.2798111 Conformation-specific infrared and ultraviolet spectroscopy of tyrosine-based protonated dipeptides 下载
10.1002/jssc.200900739 Separation of peptide diastereomers using CEC and a hydrophobic monolithic column 下载
10.1016/j.molbiopara.2012.02.003 Engagement of the S1, S1' and S2' subsites drives efficient catalysis of peptide bond hydrolysis by the M1-family aminopeptidase from Plasmodium falciparum 下载
10.1093/jn/108.7.1104 L-alanyl-L-tyrosine as a tyrosine source during intravenous nutrition of the rat 下载
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