var index = $(this).parent().parent().prevAll().length + 1;核心
<!DOCTYPE html>
<html>
<head>
<meta charset="UTF-8">
<title></title>
<script src="js/jquery-1.8.2.js"></script>
</head>
<body>
<table border="\" cellspacing="" cellpadding="">
<tr>
<th>Header1</th>
<th>Header2</th>
<th>Header3</th>
<th>Header4</th>
</tr>
<tr>
<td><input type="text" class="in1" value="11111" /></td>
<td><input type="text" class="in2" value="22222" /></td>
<td><select name="" class="sel">
<option value="1">tttt</option>
<option value="2">rrrr</option>
<option value="3">yyyy</option>
</select>
</td>
<td><input type="text" class="in3" value="44444" /></td>
</tr>
<tr>
<td><input type="text" class="in1" value="111111" /></td>
<td><input type="text" class="in2" value="222222" /></td>
<td>
<select name="" class="sel">
<option value="1">tttt</option>
<option value="2">rrrr</option>
<option value="3">yyyy</option>
</select>
</td>
<td><input type="text" class="in3" value="444444" /></td>
</tr>
<tr>
<td><input type="text" class="in1" value="1111111" /></td>
<td><input type="text" class="in2" value="2222222" /></td>
<td>
<select name="" class="sel">
<option value="1">tttt</option>
<option value="2">rrrr</option>
<option value="3">yyyy</option>
</select>
</td>
<td><input type="text" class="in3" value="4444444" /></td>
</tr>
</table>
</body>
<script>
$(function(){
var i = 0;
/* $(".in1").eq(i).on('click',function(){
alert($(".in").index(this));
$(this).parent().parent().children().eq("2").children().html('<option value="2">wwwww</option>');
})*/
$(".in1").on('click',function(){
// alert($(".in").index(this));
//找到tr后,在prevAll()
var index = $(this).parent().parent().prevAll().length + 1;
alert(index);
//$(this).parent().parent().children().eq("2").children().html('<option value="2">wwwww</option>');
})
})
</script>
</html>