python的GUI界面编程，点击开始按钮后界面就卡死怎么办？急急急

import threading
import time

def start():
    import random
    import pyautogui
    pyautogui.FAILSAFE = False
    print("按了开始键")
    global thread_stop
    thread_stop=False
    x = random.randint(-300, 300)
    y = random.randint(-300, 300)
    while thread_stop==False:
        print("未按下停止键")
        pyautogui.moveRel(x, y)
        time.sleep(5)
        if thread_stop==True:
            break


def stop():
        global thread_stop
        print("我点击了停止按钮")
        # time.sleep(5)
        thread_stop = True

def jiemian():

        import tkinter as tk

        root = tk.Tk()
        root.title("明天见")
        root.geometry("300x200")

        startButton = tk.Button(root, text='开始', bd=2, width=10, command=start)
        stopButton = tk.Button(root, text='停止', bd=2, width=10, command=stop)
        startButton.pack()
        stopButton.pack()
        root.mainloop()

if __name__ == '__main__':
    thread_stop = False
    thread1 = threading.Thread(target=start)
    thread2 = threading.Thread(target=stop)
    thread3 = threading.Thread(target=jiemian)

    thread1.start()
    thread2.start()
    thread3.start()