Dear Professor Bruss V: I am working on immunology. And one of my projects focuses on the treatment of HBV.We want to construct a vector pHBV1.5 which your used in one of your paper(Proc.Natl.Acad.Sci.USA,vol88:1059-1063).Construct this vector seems to be a problem hard to get over for us.One of my graduates has been working on it for a couple of months, but no progress. We are happy to find that your laboratory was the major source of the pHBV1.5. Therefore, I am writing to explore the possibility of getting pHBV1.5 from your laboratory. If you were kindly offering us the vector, it would be very helpful for us. Of course, the plasmid will never be used for commercial purpose.We will acknowledge the plasmid resource and cite your papers in all our publications based on the plasmid. Sure, We would like to sign any contract for the plasmid transfer. One of my graduates is waiting for the vector to set up his experiment, so your early response will be greatly appreciated.