生物信息学
傻瓜科学系列 介绍生物信息初级读物
Jean-Michel Claverie is Professor of Medical Bioinformatics at
the School of Medicine of the Université de la Méditerranée, and a
consultant in genomics and bioinformatics. He is the founder and
current head of the Structural & Genomic Information Laboratory,
located in Marseilles, a sunny city on the Mediterranean coast of
France. Using science as a pretext to travel, Jean-Michel has held
positions in Paris (France), Sherbrooke (PQ, Canada), the Salk
Institute (La Jolla, CA), the Pasteur Institute (Paris), Incyte pharmaceutical
(Palo Alto, CA); and the National Center for Biotechnology
Information (Bethesda, MD). He has used computers in biology
since the early days –– his Ph.D. work involved modeling biochemical
reactions by programming an 8K Honeywell 516 computer right
from the console switches! Although he has no clear recollection of
it, he has been credited with introducing the French word “bioinformatique”
in the late eighties, before involuntarily coining the catchy
“bioinformatics” by mistranslating it while giving a talk in English!
Jean-Michel’s current research interests are in microbial and structural
genomics, and in the development of bioinformatic methods
for the prediction of gene function. He is the author or coauthor of
more than 150 scientific publications, and a member of numerous
international review panels and scientific councils. In his spare
time, he enjoys the relaxed pace of life in Marseilles, with his wife
Chantal and their two sons, Nicholas and Raphael.
Cedric Notredame is a researcher at the French National Centre
for Scientific Research. Cedric has used and abused the facilities
offered by science to wander around Europe. After a Ph.D. at EMBL
(Heidelberg, Germany) and at the European Bioinformatics
Institute (Cambridge, UK) under the supervision of Des Higgins
(yes, the ClustalW guy), Cedric did a post-doc at the National
Institute of Medical Research (London, UK), in the lab of Willie
Taylor and under the supervision of Jaap Heringa. He then did a
post-doc in Lausanne (Switzerland) with Phillip Bucher, and
remained involved with the Swiss Institute of Bioinformatics for
several years. Having had his share of rain, snow, and wind, Cedric
has finally settled in Marseilles, where the sun and the sea are
simply warmer than any other place he has lived in.
Cedric dedicates most of his research to the multiple sequence
alignment problem and its many applications in biology. His
friends claim that his entire life (past, present, future) is somehow
stuffed into the T-Coffee multiple-sequence alignment package.
When he is not busy dismantling T-Coffee and brewing new
sequences, Cedric enjoys life in the company of his wife, Marita.