A nicely done paint package called ZBrush which has some concepts and features like dialogs in menues and being able to be dragged out to the sides to dock ('Review of the UI' video) that I would like to see in some of the future GUI design projects I'm to be involved with. Robbie, I know you are not particularly interested in UI level design like this, but feel free to put some comments if you do have some ideas.
http://www.pixologic.com/zclassroom/homeroom/tutorial.php?lesson=beginner