以下是官方回复：
英文不好的朋友请跳过这部分看下面
When you start MSN Messenger you cannot sign in, and you get the message:
Sorry, we were unable to sign you in to the MSN Messenger at this time. Please try again later.
To let us try and troubleshoot the problem, click the Troubleshoot button.
80048820
Fix this error / possible solutionThis error seems to indicate a problem with MSN Messenger's encryption routines.
The usual cause is that the time on your computer is not correct.
To correct the time on your computer, double-click the clock in the bottom right of your screen, in the window that appears you should check both the time and date.
If you use Windows XP, you can automatically correct the time by clicking the "Internet Time" tab, next click the "Update Now" button.
If you still have problems connecting with the time adjusted, try to run this file. This will make sure MSN Messenger can find all the files it needs on your computer.
Sorry, we were unable to sign you in to the MSN Messenger at this time. Please try again later.
To let us try and troubleshoot the problem, click the Troubleshoot button.
80048820
Fix this error / possible solutionThis error seems to indicate a problem with MSN Messenger's encryption routines.
The usual cause is that the time on your computer is not correct.
To correct the time on your computer, double-click the clock in the bottom right of your screen, in the window that appears you should check both the time and date.
If you use Windows XP, you can automatically correct the time by clicking the "Internet Time" tab, next click the "Update Now" button.
If you still have problems connecting with the time adjusted, try to run this file. This will make sure MSN Messenger can find all the files it needs on your computer.
基本的意思简单的说就是 你系统的时间和互联网上的时间不一致
解决办法
点右下角系统时间-确认年月日是否正确，点internet时间分页（立即更新）
确认后请登录MSN 大功告成！ 如果我帮到了您请留下你的足迹
您的回复就是我继续下去和做的更好的动力！
转载于:https://blog.51cto.com/configwater/127600
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