signature=afba2b957571d23c8d697f18a613c220,Rough Reduction Algorithm for Reduction of Metagenomic DN...

随着测序技术的发展,元基因组学迅速进步,大量未知物种的DNA序列数据涌现。当前的方法是提取成千上万的数字特征作为物种标签,但高维特征带来了计算负担。本文提出了一种结合粗糙集理论和粒子群优化算法的粗略降维方法,应用于属级别的DNA序列,实验证明能有效减少元基因组DNA特征,并提高分类准确性。
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摘要:

The renewal of sequencing technology have promoted the rapid development of metagenomics,which have lead to the sharply increasing of sequenced metagenome DNA sequences number.But most of DNA sequences species are unknown and the current method is to extract nearly ten thousands digital features as the species label,and oversize feature dimension will make large amount of calculation,so how to reduce those large metagenome DNA digital features is a problem that bioinformatics faced.A rough reduction method based on Particle Swarm Optimization(PSO) algorithm is designed which take use of rough theory and combine PSO algorithm.This algorithm have been applied to reduce the metagenome DNA sequences on the level of genera which have approved that it can make effective reduction for metagenome DNA digital features and get more classification accuracy rate than before.

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