Concept: Principal Component Analysis (PCA) is a useful technique for exploratory data analysis, allowing you to better visualize the variation present in a dataset with many variables. It is particularly helpful in the case of "wide" datasets, where you have many variables for each sample.
Well, in such cases, where many variables are present, you cannot easily plot the data in its raw format, making it difficult to get a sense of the trends present within. PCA allows you to see the overall "shape" of the data, identifying which samples are similar to one another and which are very different. This can enable us to identify groups of samples that are similar and work out which variables make one group different from another.
The mathematics underlying it are somewhat complex, so I won't go into too much detail, but the basics of PCA are as follows: you take a dataset with many variables, and you simplify that data