产品名称:二苯基环辛炔四聚乙二醇活性酯 二苯并环辛炔PEG活性酯
英文名称:DBCO-PEG4-NHS DBCO-PEG-NHS
别名:二苯并环辛炔聚乙二醇活性酯
结构式:
产品说明:二苯并环辛炔(DBCO)PEG-NHS衍生物可以在不需要任何金属催化剂的情况下进行化学反应。菌株促进的环辛炔和叠氮化合物的1,3-偶极环加成反应,也称为无铜点击反应,是一种双正交反应,可使两个分子在水溶液中共轭。
DBCO-PEG衍生物在水缓冲液中具有快速动力学和稳定性。聚乙二醇化可增加肽和蛋白质的溶解性和稳定性,并降低其免疫原性。它还可以抑制带电分子与修饰表面的非特异性结合。
Dibenzocyclooctyne (dbco) peg-nhs derivatives can be chemically reacted without any metal catalysts. The 1,3-dipolar cycloaddition reaction of cyclooctyne and azide promoted by strain, also known as copper free click reaction, is a biorthogonal reaction, which can conjugate two molecules in aqueous solution.
Dbco-peg derivatives have fast kinetics and stability in aqueous buffer. PEGylation can increase the solubility and stability of peptides and proteins, and reduce their immunogenicity. It can also inhibit the non-specific binding of charged molecules to the modified surface.
包装: 瓶装
产地:西安
温馨提示:仅供科研使用!
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作者:齐岳小编 LYQ(2023年9月11日)