Message: Access to the registry key 'Global' is denied.

具体问题请看链接：http://bbs.csdn.net/topics/390985464

最终处理方式：

1：将网站的应用池改为：DefaultAppPool。

2：选中应用池--高级设置--选择 NetworkService 或者Local System

然后就可以正常访问了。

网上找到的其他处理方式：

If you are seeing the following filling up your Sitecore log files, please following these steps to resolve the permission issue.

Exception: System.UnauthorizedAccessException
Message: Access to the registry key 'Global' is denied.
Source: mscorlib
   at Microsoft.Win32.RegistryKey.Win32Error(Int32 errorCode, String str)
   at Microsoft.Win32.RegistryKey.InternalGetValue(String name, Object defaultValue, Boolean doNotExpand, Boolean checkSecurity)
   at Microsoft.Win32.RegistryKey.GetValue(String name)
   at System.Diagnostics.PerformanceMonitor.GetData(String item)
   at System.Diagnostics.PerformanceCounterLib.GetPerformanceData(String item)
   at System.Diagnostics.PerformanceCounterLib.get_CategoryTable()
   at System.Diagnostics.PerformanceCounterLib.CategoryExists(String machine, String category)
   at System.Diagnostics.PerformanceCounterCategory.Exists(String categoryName, String machineName)
   at System.Diagnostics.PerformanceCounterCategory.Exists(String categoryName)
   at Sitecore.Diagnostics.PerformanceCounters.PerformanceCounter.CanBeCreated()
   at Sitecore.Diagnostics.PerformanceCounters.PerformanceCounter.InitializeCounter(Boolean reset)

1. Open Computer Management - System Tools - Local Users and Groups - Groups - Performance Log Users
2. Add the identity to the Performance Log Users group. The challenge is the getting the correct identity.  Check your Application Pool for the Identity.  If you are using ApplicationPoolIdentity, continue with the following steps.
3. Instead of adding a local user, ApplicationPoolIdentity is not an actual user that exists, it is virtual.  To add it, use the pattern, IIS AppPool\AppPoolName where AppPoolName is the name of the Application Pool.  For example, IIS AppPool\MySitecoreSite
4. In order for the changes to take affect, you need to either restart IIS or Stop and Start the Application Pool.  Recycling the Application Pool will not make the changes take affect.

Here is a link for more information about Application Pool Identities.