供应mPEG-DBCO，DBCO-mPEG，甲氧基-聚乙二醇-二苯基环辛炔

最新推荐文章于 2024-05-17 10:53:31 发布

PEG的工厂

最新推荐文章于 2024-05-17 10:53:31 发布

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文章标签：化学试剂

本文链接：https://blog.csdn.net/Qq__qqqqqq/article/details/129469996

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🔅基本信息🔅

中文名称：甲氧基-聚乙二醇-二苯基环辛炔

英文名称：mPEG-DBCO，DBCO-mPEG

所属分类：DBCO DBCO PEG Methoxy PEG

CAS编号：N/A

分子量：mPEG -二苯基环辛炔 1 、DBCO-mPEG 2，甲氧基-聚乙二醇-DBCO 3.4、mPEG-DBCO 5，甲氧基-聚乙二醇-二苯基环辛炔 10、mPEG-二苯基环辛炔 20

质量控制： 95%

纯度级别；分析纯AR

贮存方法：干燥，避光,-20℃

供应：陕西新研博美生物科技有限公司（货号;X-GF-0112-1K）

🔅产品结构式🔅

🔅产品简介🔅

MPEG-DBCO, also known as methoxy-PEG-DBCO, is a polyethylene glycol derivative of DBCO (dibenzocyclooctyne), which can react with azide without any metal catalyst. The 1,3-dipolar cycloaddition reaction of cyclooctyne and azide promoted by the strain, also known as copper-free click reaction, is a biological orthogonal reaction that can make two molecules conjugate in aqueous solution. PEG-DBCO derivatives have good water solubility, rapid kinetics and stability in water buffer. They are one of the PEG reagents that modify proteins, peptides, antibodies, biopolymers and particles through copper-free click chemical reactions.

mPEG-DBCO，也称为甲氧基-PEG-DBCO，是一种聚乙二醇化DBCO（二苯并环辛炔）衍生物，无需任何金属催化剂即可与叠氮化物发生反应。菌株促进的环辛炔和叠氮化合物的1,3-偶极环加成反应，也称为无铜点击反应，是一种生物正交反应，可使两个分子在水溶液中共轭。PEG-DBCO衍生物具有良好的水溶性，在水缓冲液中具有快速动力学和稳定性。它们是通过无铜点击化学反应修饰蛋白质、肽、抗体、生物聚合物和颗粒的聚乙二醇化试剂之一。

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