Pyrene酰肼，Pyrene hydrazide，激发态具有超过100纳秒的寿命

文章关键词：Pyrene hydrazide，Pyrene酰肼，芘酰肼

一、基本信息

【性质简介】：Pyrene, a blue fluorescent marker, is like a brilliant pearl in the field of scientific research. Its function as a proximity probe is particularly prominent, as it can accurately reveal the interactions and distance changes between biomolecules. When two pyrene residues approach each other in space, they exhibit a stunning quasi molecular fluorescence phenomenon with a longer wavelength, allowing researchers to observe subtle changes between molecules more intuitively. Pyrene also has the potential to serve as a FRET donor for other fluorescent groups. In the study of fluorescence resonance energy transfer (FRET), pyrene can transfer the energy of its excited state to adjacent fluorescent groups, thereby achieving efficient energy transfer and conversion. This characteristic makes pyrene have broad application prospects in fields such as biological imaging, drug screening, and molecular probes. In addition, the excited state lifetime of pyrene is exceptionally long, exceeding 100 nanoseconds, making it an ideal fluorescent group in time gated experiments. In time gated experiments, researchers can observe the fluorescence changes of fluorescent groups at different time points by precisely controlling the switching time of the light source, thereby revealing the dynamic interaction process between biomolecules.

【中文名】：Pyrene酰肼，芘酰肼

【英文名】：Pyrene hydrazide

【化学式】：C20H19ClN2O

【分子量】：338.83

【结构式】：

 

​二、详情介绍

【外观】：固体/粉末

【溶解性】：溶于大部分有机溶剂

【规格】：10mg、25mg、50mg

【纯度】：95%+

【储存条件】：本品应密封避光，储存于阴凉、干燥、通风处，避免反复冻融，储液应该立即使用

【注意事项】：试剂仅用于科学研究或者工业应用等非医疗目的，非药用，非食用！

三、相关试剂

NOTA-Maleimide

NOTA-Tetrazine

NOTA-NHS ester

NOTA-(COOt-Bu)2

MeTz-PEG11-NOTA

DOTA-SH，DOTA-巯基

DOTA Methyltetrazine，DOTA甲基四嗪

DOTA-4AMP，1,4,7,10-四氮杂十二烷基十二烷基醚-1,4,7,10-四(乙酰胺基-亚甲基膦酸)

DOTA-PEG4-MeTz ，DOTA-四聚乙二醇-甲基四嗪

DOTA-tris(t-Bu ester)，三叔丁基1,4,7,10-四氮杂环十二烷-1,4,7,10-四乙酸

DOTA-PEG5-DBCO ，DOTA五聚乙二醇二苯并环辛炔

DOTA-PEG5-azide，DOTA五聚乙二醇叠氮

DOTA-PEG5-amine

DOTA-Acrylamide，DOTA-丙烯酰胺

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