They did not give the virus an easy jerseys
The researchers developed a virus Delta-24-RGD for the express purpose of working on a molecular weakness that was noticed to occur in tumors. They then changed the virus a bit, making it impossible for the virus to replicate itself in normal, healthy tissues. They tested the altered virus in mice and the results of that experiment showed that the virus as able to completely eradicate the tumors in 60 nfl jerseys cheap% of the mice. They do this by injecting the virus right into the tumor itself. The virus spreads itself throughout the tumor until it has destroyed all the cancer cells and then it dies. In the next phase of the experiment, the researchers obtained four specimens of glioblastoma multiforme tumors. From these tumors, they were able to obtain four different stem cell world cup jerseys lines, all of which had the same properties as stem cells. The Delta-24 virus was able to kill every one of the four different lines. When this phase proved to be successful, they went on to the next step, again with the mice, This time they grafted the lines of stem cells right into the mice brains and then treated the tumors that resulted with the injections of Delta-24-RGD. There were two groups of mice, one was treated and one was not. The untreated mice had an average survival rate of 38.5 days. The mice who got the trea straightenerstments survived for an average of 66 days. There were 8 mice who were treated and two of them survived for the full 92 days of the experiment and more importantly, they did not exhibit any neurological problems. One reason that they have such high expectations for this treatment is the great similarity in the mouse tumors with the corresponding tumors in humans. Normally, the mouse tumors are round, whereas human tumors tend to be irregularly shaped. In this case, the tumors are the same shape, showing that there is a great possibility to duplicate the success in humans. They are submitting a request to the federal regulators later this month for permission to start a clinical trial in humans. The team is being led by Juan Fueyo, M.D., associate professor in M. D. Anderson's Department of Neuro-Oncology, co-senior author Frederick Lang, M.D., professor in M. D. Anderson's Department of Neurosurgery, and first author Hong Jiang, Ph.D., instructor in neuro-oncology. The rest of the team and co- authors of the study are wholesale nba jerseys. Candelari Gomez-Manzano, Hiroshi Aoki, Marta Alonso, Seiji Kondo, Jing Xu, Yasuku Kondo, and Howard Colman, all of the M. D. Anderson Brain Tumor Center; B. Nebiyou Bekele, of M. D. Anderson's Department of Biostatistics; and Frank McCormick, Cancer Research Institute and Comprehensive Cancer Center, University of California, San Francisco. Aoki also is affiliated with the Department of Neurosurgery, Brain Research Institute, Niigata University in Niigata, Japan Not all viruses are bad. Many of them are just the opposite, like the one that researchers at The University of Texas M. D. nba jerseys shop Anderson Cancer Center have been able to specially tailor to destroy stem cells in brain tumors. These cells have not responded to any other form. of treatment and they are responsible for re occurrence of cancer after surgery. They did not give the virus an easy test. They put it up against one of the most serious and aggressive of all of the brain tumors, one called glioblastoma multiforme. This particular tumor originates in the glial cells. These cells provide support and protection for neurons in the central nervous system. They surround the neurons and are supposed to give them support. This particular tumor has been found to be extremely resistant to both radiation and chemotherapy and it is such an i hockey jerseysnvasive class of tumor, that it is very rare when surgery is successful. Anyone who is diagnosed with this type of cancer can expect to live for 14 months or so and that is with the current treatments that are available.
The researchers developed a virus Delta-24-RGD for the express purpose of working on a molecular weakness that was noticed to occur in tumors. They then changed the virus a bit, making it impossible for the virus to replicate itself in normal, healthy tissues. They tested the altered virus in mice and the results of that experiment showed that the virus as able to completely eradicate the tumors in 60 nfl jerseys cheap% of the mice. They do this by injecting the virus right into the tumor itself. The virus spreads itself throughout the tumor until it has destroyed all the cancer cells and then it dies. In the next phase of the experiment, the researchers obtained four specimens of glioblastoma multiforme tumors. From these tumors, they were able to obtain four different stem cell world cup jerseys lines, all of which had the same properties as stem cells. The Delta-24 virus was able to kill every one of the four different lines. When this phase proved to be successful, they went on to the next step, again with the mice, This time they grafted the lines of stem cells right into the mice brains and then treated the tumors that resulted with the injections of Delta-24-RGD. There were two groups of mice, one was treated and one was not. The untreated mice had an average survival rate of 38.5 days. The mice who got the trea straightenerstments survived for an average of 66 days. There were 8 mice who were treated and two of them survived for the full 92 days of the experiment and more importantly, they did not exhibit any neurological problems. One reason that they have such high expectations for this treatment is the great similarity in the mouse tumors with the corresponding tumors in humans. Normally, the mouse tumors are round, whereas human tumors tend to be irregularly shaped. In this case, the tumors are the same shape, showing that there is a great possibility to duplicate the success in humans. They are submitting a request to the federal regulators later this month for permission to start a clinical trial in humans. The team is being led by Juan Fueyo, M.D., associate professor in M. D. Anderson's Department of Neuro-Oncology, co-senior author Frederick Lang, M.D., professor in M. D. Anderson's Department of Neurosurgery, and first author Hong Jiang, Ph.D., instructor in neuro-oncology. The rest of the team and co- authors of the study are wholesale nba jerseys. Candelari Gomez-Manzano, Hiroshi Aoki, Marta Alonso, Seiji Kondo, Jing Xu, Yasuku Kondo, and Howard Colman, all of the M. D. Anderson Brain Tumor Center; B. Nebiyou Bekele, of M. D. Anderson's Department of Biostatistics; and Frank McCormick, Cancer Research Institute and Comprehensive Cancer Center, University of California, San Francisco. Aoki also is affiliated with the Department of Neurosurgery, Brain Research Institute, Niigata University in Niigata, Japan Not all viruses are bad. Many of them are just the opposite, like the one that researchers at The University of Texas M. D. nba jerseys shop Anderson Cancer Center have been able to specially tailor to destroy stem cells in brain tumors. These cells have not responded to any other form. of treatment and they are responsible for re occurrence of cancer after surgery. They did not give the virus an easy test. They put it up against one of the most serious and aggressive of all of the brain tumors, one called glioblastoma multiforme. This particular tumor originates in the glial cells. These cells provide support and protection for neurons in the central nervous system. They surround the neurons and are supposed to give them support. This particular tumor has been found to be extremely resistant to both radiation and chemotherapy and it is such an i hockey jerseysnvasive class of tumor, that it is very rare when surgery is successful. Anyone who is diagnosed with this type of cancer can expect to live for 14 months or so and that is with the current treatments that are available.
来自 “ ITPUB博客 ” ，链接：http://blog.itpub.net/23986545/viewspace-663864/，如需转载，请注明出处，否则将追究法律责任。
转载于:http://blog.itpub.net/23986545/viewspace-663864/
209
被折叠的 条评论
为什么被折叠?
到【灌水乐园】发言
