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生物信息学
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nicole_Qi
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全基因组尺度的增强子--靶基因映射图谱解码非编码突变
Genome-wide enhancer maps link risk variants to disease genes文章目录Genome-wide enhancer maps link risk variants to disease genes前言1.Overview of approach2.Enhancer-gene connections3.CRISPRi-FlowFISH4.ABC model5.The ABC model is generally applicable across ce原创 2021-05-27 15:33:04 · 1640 阅读 · 0 评论 -
【Nature | EpiMap】Regulatory genomic circuitry of human disease loci by integrative epigenomics
Regulatory genomic circuitry of human disease loci by integrative epigenomics文章目录Regulatory genomic circuitry of human disease loci by integrative epigenomics前言1.EpiMap: Methodological overview and contributions2.Combined resource: 14,000+ datasets across原创 2021-03-16 17:20:20 · 894 阅读 · 1 评论 -
【CELL 心脏时空图】A spatiotemporal organ-wide gene expression and cell atlas of the developing human heart
A spatiotemporal organ-wide gene expression and cell atlas of the developing human heart文章目录A spatiotemporal organ-wide gene expression and cell atlas of the developing human heart前言1.文章框架2.取样3.免疫组化4.空间转录组5.单细胞测序6.原位测序前言今天讲的是2020年发表在cell的人类心脏发育的时空器官全原创 2020-12-30 19:10:39 · 1206 阅读 · 0 评论 -
【Paper reading】BENGI & Measuring the reproducibility and quality of Hi-C data
可变剪接预测&ENCODEC数据集1. A curated benchmark of enhancer-gene interactions for evaluating enhancer-target gene prediction methods2. Measuring the reproducibility and quality of Hi-C data文章目录可变剪接预测&ENCODEC数据集1. A curated benchmark of enhancer-gene int原创 2020-11-07 17:40:37 · 392 阅读 · 0 评论 -
【Paper reading】可变剪接预测&ENCODEC数据集
两篇基于Encode项目的论文 Paper reading1. Epigenome-based splicing prediction using a recurrent neural network2. An integrative ENCODE resource for cancer genomics文章目录两篇基于Encode项目的论文 Paper reading1. Epigenome-based splicing prediction using a recurrent neural net原创 2020-09-18 12:06:39 · 2159 阅读 · 0 评论