利用WPF中的Grid控件对窗体控件进行布局。

<Window x:Class="WpfApp1.MainWindow"
        xmlns="http://schemas.microsoft.com/winfx/2006/xaml/presentation"
        xmlns:x="http://schemas.microsoft.com/winfx/2006/xaml"
        xmlns:d="http://schemas.microsoft.com/expression/blend/2008"
        xmlns:mc="http://schemas.openxmlformats.org/markup-compatibility/2006"
        xmlns:local="clr-namespace:WpfApp1"
        mc:Ignorable="d"
        Title="留言板" Height="450" Width="800">
    <Grid Margin="10" >
        <Grid.RowDefinitions>
            <RowDefinition Height="25"/>
            <RowDefinition Height="4"/>
            <RowDefinition Height="*"/>
            <RowDefinition Height="4"/>
            <RowDefinition Height="25"/>
        </Grid.RowDefinitions>
        <Grid.ColumnDefinitions>
            <ColumnDefinition Width="Auto"/>
            <ColumnDefinition Width="*"/>
            <ColumnDefinition Width="80" />
            <ColumnDefinition Width="4"/>
            <ColumnDefinition Width="80"/>
        </Grid.ColumnDefinitions>

        <TextBlock Text="请选择您的部门并留言：" Grid.Column="0" Grid.Row="0" VerticalAlignment="Center"/>
        <ComboBox Grid.Column="1" Grid.ColumnSpan="4" Grid.Row="0" />
        <TextBox Text="根据内容自动调整" Grid.Column="0" Grid.ColumnSpan="5" Grid.Row="2" BorderBrush="Black"/>
        <Button Content="提交" Grid.Column="2" Grid.Row="4"/>
        <Button Content="清除" Grid.Column="4" Grid.Row="4"/>
    </Grid>
</Window>