python出现 ValueError: could not convert string to float: '75,871.62' 字符中间带逗号如何转换为浮点型

如何去掉数字字符串里面的逗号
float转化str时str不能为空,不能带有’\n’
否则就会报错ValueError: could not convert string to float:

f = open("C:/Users/24224/Documents/Tencent Files/2422443606/FileRecv/fp.txt")
s = f.read()
a = list(s.split("\n"))
for i in range(len(a)):
    a[i]=a[i].replace(',','')
dfp = []
for i in range(len(a)):
    if i+1<len(a):
        c=float(a[i])
        d=float(a[i+1])
        dfp.append(c - d)
print(dfp)

计算协方差,相关系数矩阵

import numpy
f = open("C:/Users/24224/Documents/Tencent Files/2422443606/FileRecv/fp.txt")
h = open("C:/Users/24224/Documents/Tencent Files/2422443606/FileRecv/sp.txt")
s = f.read()
g = h.read()
a = list(s.split("\n"))
b = list(g.split("\n"))
for i in range(len(a)):
    a[i] = float(a[i].replace(",", ""))
    b[i] = float(b[i].replace(",", ""))
dfp = []
dsp = []
for i in range(len(a)-1):
    dfp.append(a[i]-a[i+1])
    dsp.append(b[i]-b[i+1])
stf = numpy.std(a, ddof=1)
sts = numpy.std(b, ddof=1)
xgx = numpy.corrcoef(a, b)[0][1]
ans = xgx*sts/stf
print(dfp)
print(dsp)
print(xgx)
print(sts)
print(stf)
print(ans)