部分数据库功能介绍
MethCGI
Applied Biosystems simplify DNA methylation with free software: Applied Biosystems simplify DNA methylation with free software.The software, known as Methyl Primer Express, specifically automates the design of methylation-specific PCR or bisulphite sequencing primers as well as the methylSEQr Bisulphite Conversion Kit, a set of prepackaged reagents for rapid bisulphite conversion.Together these products simplify applications such as bisulphite sequencing and fragment analysis in DNA methylation experiments.(http://www.drugresearcher.com/news-by-product/news.asp?id=71445&idCat=43&k=Applied-Biosystems--DNA-methylation-DNA-polymerases)
Illumina Introduces Genome-Wide DNA Methylation Profiling Using Highly Acclaimed Infinium(R) Assay: Illumina Introduces Genome-Wide DNA Methylation Profiling Using Highly Acclaimed Infinium(R) Assay.SAN DIEGO--(BUSINESS WIRE)--Illumina, Inc. (NASDAQ:ILMN - News) today introduced a 12-sample Infinium DNA Methylation BeadChip for use in epigenetic research. With this new high-density solution, researchers can assay approximately 27,000 CpG sites per sample, covering more than 14,000 well-annotated genes with single CpG resolution. Content for this panel was derived from genes described in the National Center for Biotechnology Information (NCBI) Consensus Coding Sequence (CCDS) Database, and features a core set of protein-coding regions that are consistently annotated and of high quality. In addition, the new array includes more than 1,000 cancer-related genes and 200 CpG sites located within CpG islands found in promoter regions of microRNA (miRNA) genes. Full commercial shipments of Illumina’s Infinium DNA Methylation Panel are expected for Q1 2008.(http://biz.yahoo.com/bw/071025/20071025005491.html?.v=1)
SubMito
SubMito is the first computational system for predicting protein submitochondria locations from its primary sequence. SubMito is designed and implemented with Java. This site is a web-like front end for SubMito system. Users can access SubMito on the server side by uploading a FASTA file or entering sequence below. The prediction result will be saved on server, and a link to the result file will be provided. Users can use this link to download the result file.