In the below network topology a web server behind a router is on private IP address space, and the router performs NAT to forward traffic to its public IP address to the web server behind it.
The NAT configuration would look like below:
/ip firewall natadd chain=dstnat dst-address=1.1.1.1 protocol=tcp dst-port=80 \ action=dst-nat to-address=192.168.1.2add chain=srcnat out-interface=WAN action=masquerade
When a client out on the Internet with IP address 2.2.2.2 establishes a connection to the web server, the router performs NAT as configured.