首先添加引用: using System.Web.Configuration; 加密操作如下: private void ProtectSection( string sectionName, string provider) { Configuration config = WebConfigurationManager. OpenWebConfiguration(Request.ApplicationPath); ConfigurationSection section = config.GetSection(sectionName); if (section != null && !section.SectionInformation.IsProtected) { section.SectionInformation.ProtectSection(provider); config.Save(); } } 解密操作如下: private void UnProtectSection( string sectionName) { Configuration config = WebConfigurationManager. OpenWebConfiguration(Request.ApplicationPath); ConfigurationSection section = config.GetSection(sectionName); if (section != null && section.SectionInformation.IsProtected) { section.SectionInformation.UnprotectSection(); config.Save(); } } 实践: 加密前的配置文件: <? xml version="1.0" ?> < configuration > < appSettings > < add key ="name" value ="shy520" /> < add key ="address" value ="cnblogs" /> </ appSettings > < system .web > < compilation debug ="true" /> </ system.web > </ configuration > 加密后的配置文件: <? xml version="1.0" ?> < configuration > < appSettings configProtectionProvider ="DataProtectionConfigurationProvider" > < EncryptedData > < CipherData > < CipherValue > AQAAANCMnd8BFdERjHoAwE/Cl+s BAAAABi1ATlNkEUGEf0XyWGL2Xg QAAAACAAAAAAADZgAAqAAAABAAA ABIhxMWlazAntwIIpST1CDXAAAA AASAAACgAAAAEAAAAPz/YKYx07c b+h4fqdr4fkLgAAAAX1Ieyc+WSx AfsDW1vn2C/fXsG2TAnYeUgaCov 8e3nGFTHHsH91gLiqKregFPYzGR vW1xrez/3VwOmJI9eS7EFKrcXej NnHL66kg2iNRk3ntLNZlZtTs3cZ 9w63u47VKAjs6miWsGBz2GntL/9 UGHLELigrJcr3YJ+lsjOscExQnv HGvA48EfxpD+tEiFBtgXeHsFkQX cqGySshx16vCt2GUNUC3ZmEAhBh UsAFkPIYqelYHd4+m9a/xPe2tqw GIbla1wbW2NDEfrzJPwnkfmpNqR hXijKImipwXbDVYy6o0UAAAAs8D suYNOhJ7qAjJa2c/4eUC7sks= </ CipherValue > </ CipherData > </ EncryptedData > </ appSettings > < system .web > < compilation debug ="true" /> </ system.web > </ configuration >