HHS Public Access
Author manuscript
A Annu Rev Psychol . Author manuscript; available in PMC 2016 March 08.
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Published in final edited form as:
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r Annu Rev Psychol . 2016 January 4; 67: 613–640. doi:10.1146/annurev-psych-122414-033634.
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Modular Brain Networks
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t Olaf Sporns1,2 and Richard F. Betzel1
1Department of Psychological and Brain Sciences, Indiana University, Bloomington, Indiana
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2 Indiana University Network Science Institute, Indiana University, Bloomington, Indiana 47405
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Abstract
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o The development of new technologies for mapping structural and functional brain connectivity has
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M led to the creation of comprehensive network maps of neuronal circuits and systems. The
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n architecture of these brain networks can be examined and analyzed with a large variety of graph
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s theory tools. Methods for detecting modules, or network communities, are of particular interest
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i because they uncover major building blocks or subnetworks that are particularly densely
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t connected, often corresponding to specialized functional components. A large number of methods
for community detection have become available and are now widely applied in network
neuroscience. This article first surveys a number of these methods, with an emphasis on their
advantages and shortcomings; then it summarizes major findings on the existence of modules in
both structural and functional brain networks and briefly considers their potential functional roles
in brain