TabControl控件的加入关闭按钮

首先需要将 绘制模式修改成 自定义模式
只有DrawMode等于OwnerDrawFixed时，才会在绘制选项卡时发生DrawItem事件

tabControl1.DrawMode = TabDrawMode.OwnerDrawFixed;

注册事件

const int CLOSE_SIZE = 12;// 定义范围大小
 private void tabControl1_DrawItem(object sender, DrawItemEventArgs e)//DrawItem事件
        {
            try
            {
                标签背景填充颜色
                SolidBrush BackBrush = new SolidBrush(Color.FromArgb(5, 131, 205));
                //标签文字填充颜色
                SolidBrush FrontBrush = new SolidBrush(Color.Black);



                //获取当前Tab选项卡的绘图区域
                Rectangle myTabRect = this.tabControl1.GetTabRect(e.Index);

                //绘制标签头背景色
                using (Brush brBack = new SolidBrush(Color.White))
                {
                    if (e.Index == this.tabControl1.SelectedIndex)
                    {
                        e.Graphics.FillRectangle(brBack, myTabRect); //设置当前选中的tabgage的背景色
                    }
                }

                StringFormat StringF = new StringFormat();
                //设置文字对齐方式
                StringF.Alignment = StringAlignment.Near;
                StringF.LineAlignment = StringAlignment.Center;
                for (int i = 0; i < tabControl1.TabPages.Count; i++)
                {
                    //获取标签头工作区域
                    Rectangle Rec = tabControl1.GetTabRect(i);
                    if (tabControl1.SelectedIndex == i)//选中的item更改颜色
                    {
                        //绘制标签头文字
                        e.Graphics.DrawString(tabControl1.TabPages[i].Text, new Font("微软雅黑", 11), FrontBrush, Rec, StringF);
                    }
                    else
                    {
                        //绘制标签头背景颜色
                        //e.Graphics.FillRectangle(BackBrush, Rec);
                        e.Graphics.DrawString(tabControl1.TabPages[i].Text, new Font("微软雅黑", 11), FrontBrush, Rec, StringF);
                    }
                }

                //先添加TabPage属性
                //e.Graphics.DrawString(this.tabControl1.TabPages[e.Index].Text, this.Font, SystemBrushes.ControlText, myTabRect.X + 2, myTabRect.Y + 2);


                //再画一个矩形框
                using (Pen p = new Pen(Color.Transparent))
                {
                    myTabRect.Offset(myTabRect.Width - (CLOSE_SIZE + 3), 2);
                    myTabRect.Width = CLOSE_SIZE;
                    myTabRect.Height = CLOSE_SIZE;
                    e.Graphics.DrawRectangle(p, myTabRect);
                }
                //填充矩形框
                Color recColor = (e.State == DrawItemState.Selected) ? Color.Transparent : Color.Transparent;
                using (Brush b = new SolidBrush(recColor))
                {
                    e.Graphics.FillRectangle(b, myTabRect);
                }

                //画Tab选项卡右上方关闭按钮   
                using (Pen objpen = new Pen(Color.Red, 1.8f))
                {
                    //自己画X
                    //"\"线
                    Point p1 = new Point(myTabRect.X + 10, myTabRect.Y + 10);
                    Point p2 = new Point(myTabRect.X + myTabRect.Width - 10, myTabRect.Y + myTabRect.Height - 10);
                    e.Graphics.DrawLine(objpen, p1, p2);
                    //"/"线
                    Point p3 = new Point(myTabRect.X + 10, myTabRect.Y + myTabRect.Height - 10);
                    Point p4 = new Point(myTabRect.X + myTabRect.Width - 10, myTabRect.Y + 10);
                    e.Graphics.DrawLine(objpen, p3, p4);


                    使用图片
                    //Bitmap bt = new Bitmap(image);
                    //Point p5 = new Point(myTabRect.X, 4);//获取绘图区域的开始坐标位置
                    //e.Graphics.DrawImage(bt, p5);
                }
                e.Graphics.Dispose();
            }
            catch (Exception)
            {

            }
        }
//鼠标点击事件
        private void tabControl1_MouseDown(object sender, MouseEventArgs e)
        {
            if (this.tabControl1.TabCount == 0)
            {
                return;
            }

            if (!String.IsNullOrEmpty(this.tabControl1.SelectedTab.Text))
            {
                if (e.Button == MouseButtons.Left)
                {
                    int x = e.X, y = e.Y;

                    //计算关闭区域      
                    Rectangle myTabRect = this.tabControl1.GetTabRect(this.tabControl1.SelectedIndex); ;

                    myTabRect.Offset(myTabRect.Width - 0x12, 2);
                    myTabRect.Width = CLOSE_SIZE;
                    myTabRect.Height = CLOSE_SIZE;

                    //如果鼠标在区域内就关闭选项卡      
                    bool isClose = x > myTabRect.X && x < myTabRect.Right && y > myTabRect.Y && y < myTabRect.Bottom;
                    if (isClose == true)
                    {
                        this.tabControl1.TabPages.Remove(this.tabControl1.SelectedTab);

                    }
                }
            }
        }
  

绑定事件

 this.tabControl1.DrawItem += tabControl1_DrawItem;
this.tabControl1.MouseDown += tabControl1_MouseDown;

另外操作关于 tabpage标签大小的操作
SizeMode属性设为Fixed 然后设置ItemSize的大小就可以了
new size（80,20）
其中设置问题

参考地址：https://www.cnblogs.com/zhang-rui/p/13209207.html