signature=4ffe3dea09219eb1d7153aee99be3fd5,Therapeutically effective ω-(4-(2-pyridyl)-piperazino)-al...

摘要:

The ω-[4-(2-pyridyl)-piperazino]-alkanoylanilide compounds having the structural formula (I): ##STR1## wherein n is 1, 2 or 3, each of R, R, RR, and Ris independently hydrogen, halogen, alkyl, alkoxy, OH, NH, CF, CN, alkylthio, 1-hydroxyalkyl, alkanoyl, NHCO, NHSO, alkoxycarbonyl, alkylsulfonyl, benzyloxy, alkanoylamino, NHCONH, 3-phenylureido, 3-alkylureido or alkoxyoxalylamino, Ris hydrogen or alkyl, and Ris hydrogen or alkoxy, and the pharmaceutically acceptable salts thereof, are effective antianaphylactics, antibronchospastics, antihistaminics, sedatives, analgesics, antiserotonics and blood-pressure-lowering agents.

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