【工具】SpectroPipeR精简后Spectronaut®DIA-MS数据分析R包

本文链接：https://blog.csdn.net/H20230717/article/details/146033863

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介绍

由于生物信息学资源有限，数据生成快速，分析方法多变，蛋白质组学研究在下游数据分析中经常遇到挑战。为了解决这些问题，我们开发了SpectroPipeR，这是一个R软件包，旨在简化数据分析任务，并为Spectronaut®DIA-MS数据提供全面、标准化的管道。这个新颖的软件包自动化各种分析过程，包括XIC图，ID率总结，归一化，批处理和协变量调整，相对蛋白质定量，多变量分析和统计分析，同时生成交互式HTML报告，例如ELN系统。

Abstract
Summary
Proteome studies frequently encounter challenges in down-stream data analysis due to limited bioinformatics resources, rapid data generation, and variations in analytical methods. To address these issues, we developed SpectroPipeR, an R package designed to streamline data analysis tasks and provide a comprehensive, standardized pipeline for Spectronaut® DIA-MS data. This novel package automates various analytical processes, including XIC plots, ID rate summary, normalization, batch and covariate adjustment, relative protein quantification, multivariate analysis, and statistical analysis, while generating interactive HTML reports for e.g. ELN systems.