LAG-3全称为淋巴细胞活化基因3(Lymphocyte Activation Gene-3),又称CD223,在T细胞活化的负调控以及稳态增殖方面起重要作用。LAG-3与T细胞共受体CD4密切相关,并与MHC II类分子结合,但结合MHCII比CD4具有更高亲和力。LAG-3在肿瘤免疫治疗方面存在巨大潜力。
产品详情:
别名:Lymphocyte Activation Gene-3; FDC Protein; CD223
类型:Monoclonal Antibody
来源:Purified from concentrated hybridoma tissue culture supernatant.
应用:ELISA
偶联:Biotin
克隆号:17B4
免疫原:Synthetic peptide corresponding to 30 aa in the N-terminus of human LAG-3.
同种型:Mouse IgG1kappa
浓度:1mg/ml
品牌:Adipogen
供应商:欣博盛生物
该产品自上市以来有多篇文献引用,品质有保证,以下是最新发表的文献引用:
1.Human dendritic cells acquire a semimature phenotype and lymph node homing potential through interaction with CD4+CD25+ regulatory T cells: J. Bayry, et al.; J. Immunol. 178, 4184 (2007)
2.Human lymphocyte activation gene-3 molecules expressed by activated T cells deliver costimulation signal for dendritic cell activation: C. Casati, et al.; J. Immunol. 180, 3782 (2008)
订购信息:
品牌 代理商 产品名称 产品货号 规格
Adipogen 欣博盛生物 anti-LAG-3 (human), mAb (17B4) (Biotin) AG-20B-0012B-C100 100 ug