6-TAMRA Mal，6-TAMRA maleimide，可以和巯基发生亲和加成反应

文章关键词：6-TAMRA maleimide，6-TAMRA Mal，四甲基罗丹明马来酰亚胺，1192590-89-8

一、基本信息

【性质简介】：The maleimide group in 6-TAMRA maleimide is a brilliant gem in biomarker reactions. It attracts thiol groups (- SH) with its unique affinity and weaves stable thioester structures through affinity addition reactions, providing a solid foundation for biomarkers. This reaction mechanism is not only precise but also efficient, making the biomarker process more reliable and controllable. In living organisms, although amino groups (such as the side chains of lysine and arginine) also have a certain affinity, the selectivity of maleimide towards thiol groups is particularly prominent in neutral or slightly acidic buffer solutions. In fact, the reaction rate between maleimide and thiol group is more than 1000 times faster than that with amino group. This astonishing difference in reaction rates enables maleimide to accurately locate and label thiol groups in complex biological environments, providing strong support for biomarker experiments.

【中文名】：四甲基罗丹明马来酰亚胺

【英文名】：6-TAMRA maleimide，6-TAMRA Mal

【CAS号】：1508249-06-6

【化学式】：C31H28N4O6

【分子量】：552.58

【结构式】：

二、详情介绍

【外观】：固体/粉末

【溶解性】：溶于大部分有机溶剂

【规格】：10mg、25mg、50mg（接受各种规格的定制服务，具体可以线上咨询）

【纯度】：95%+

【储存条件】：本品应密封避光，储存于阴凉、干燥、通风处，避免反复冻融，储液应该立即使用

【注意事项】：陕西新研博美生物科技有限公司提示，试剂仅用于科学研究或者工业应用等非医疗目的，非药用，非食用！

三、相关试剂

CAS：2071694-39-6，5-TAMRA-DBCO

CAS：91809-67-5，6-Carboxytetramethylrhodamine，6-TAMRA

CAS：1006592-61-5，5-TAMRA-C6-azide

CAS：2183440-67-5，TAMRA hydrazide,6-isomer，6-TAMRA-hydrazide

CAS：2158336-47-9 (inner salt)，TAMRA amine,5-isomer，5-TAMRA-NH2

CAS：150810-69-8，6-TAMRA NHS ester，6-TAMRA-SE

CAS：1426090-03-0，SiR-COOH

CAS：2296718-56-2，SiR-Maleimide

CAS：1808181-14-7，SiR-NHS ester

CAS：915013-10-4，TRITC Phalloidin

本文整理分享来自于小编zmy