The best way to deal with large files in Python style

<span style="font-family:Arial Black;font-size:12px;color:#000099;">with open(...) as f:
    for line in f:
        <do something with line></span>

The with statement handles opening and closing the file, including if an exception is raised in the inner block. The for line in f treats the file object f as an iterable, which automatically uses buffered IO and memory management so you don't have to worry about large files.

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Another alternative: by making use of yield.

<span style="font-family:Arial Black;font-size:12px;">def read_file(fpath): 
    BLOCK_SIZE = 1024 
    with open(fpath, 'rb') as f: 
        while True: 
            block = f.read(BLOCK_SIZE) 
            if block: 
                yield block 
            else: 
                return</span>

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