蛋白质亚硝基化修饰位点预测工具 —— GPS-SNO 1.0

最新推荐文章于 2023-04-16 20:51:47 发布

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最新推荐文章于 2023-04-16 20:51:47 发布

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分类专栏： 01.Publications 文章标签：工具 performance algorithm transition validation system

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GPS-SNO: Computational prediction of protein S -nitrosylation sites with a modified GPS algorithm. Yu Xue , Zexian Liu, Xinjiao Gao, Changjiang Jin, Longping Wen, Xuebiao Yao, and Jian Ren . Plos One . 2010;5(6):e11290 [Full Text] [PDF]

The 1998 Nobel Prize in Physiology or Medicine was awarded for seminal discoveries that nitric oxide (NO) is a freely-diffusible signalling molecule and second messenger, regulates the production of cyclic GMP (cGMP), and plays essential roles in the cardiovascular system. Later, flood of studies challenged this fundamental view by observing that NO could spatially and temporally target specific cysteine thiols and transition metals of proteins, a reversibly post-translational modification (PTM) termed as