VSTO
using System; using System.Collections.Generic; using System.Linq; using System.Text; using System.Xml.Linq; using Excel = Microsoft.Office.Interop.Excel; using Office = Microsoft.Office.Core; using Microsoft.Office.Tools.Excel; using System.Reflection; namespace VSTO { public partial class ThisAddIn { private void ThisAddIn_Startup(object sender, System.EventArgs e) { //Add a new workbook Excel.Workbook excelApp = this.Application.Workbooks.Add(); //Protect the worksheet with password ((Excel.Worksheet)excelApp.ActiveSheet).Protect("Spire"); //Unprotect the worksheet specifying its password